How To Store Trimix Injections To Preserve Potency

Proper storage of any medication is crucial in maintaining its potency and safety. This is because environmental factors such as temperature, humidity, and light exposure can affect the chemical composition of the medication, leading to degradation and potential health risks. This is especially important for medications that are used for conditions like erectile dysfunction, where potency is essential for their effectiveness. For example, Trimix injections, which are commonly used for this purpose, need to be stored correctly to ensure maximum potency and safety. The following guide explains how you should store Trimix injections for optimal results.

An Overview Of Trimix Injections

Trimix injections contain alprostadil which has been FDA approved for the treatment of erectile dysfunction (ED). Additionally they papaverine, and phentolamine. These medications work together to dilate the blood vessels in the penis. As a result, blood flow will increase, thus helping with achieving and maintaining an erection. The solution must be injected directly into the penis to produce an erection. 

It’s important to note that Trimix is a compound medication. Compound medications are unavailable in commercial pharmacies and must be specially formulated by a compounding pharmacy. This allows for customized and precise dosing based on individual needs. However, like all medications, Trimix injections must be stored properly to ensure maximum potency and safety.

Factors Affecting Trimix Sensitivity

Trimix injections are sensitive to environmental factors that can affect their potency and safety. These include:

  • Temperature and light exposure: Exposure to heat and light can cause Trimix to degrade. This is because the chemical bonds within the medication’s molecules can be disrupted by overexposure to heat and light, altering their composition and potentially decreasing their effectiveness. The ideal temperature for storing Trimix is from 36°F to 46°F (2°C to 8°C), and it should be kept away from direct light.
  • Air and moisture sensitivity: Trimix is also sensitive to air and moisture. Exposure to these elements can cause oxidation, which can change the medication’s chemical structure and decrease its potency. To prevent this, Trimix injections should be stored in airtight containers and kept away from areas with high humidity.
  • Shelf life considerations: Like most medications, Trimix injections have a limited shelf life. It is essential to check the beyond-use date (BUD) provided by the compounding pharmacy and ensure that you use the medication before it expires. Using expired Trimix injections can lead to reduced effectiveness and potential health risks.

Importance Of Proper Storage For Injection Effectiveness And Safety

Proper storage of Trimix injections is crucial for maintaining their potency and ensuring safety during use. Any degradation or changes in the medication’s chemical composition can affect its effectiveness, leading to unsatisfactory results. Additionally, expired or improperly stored Trimix injections may cause adverse reactions and potential health risks. 

Best Practices In Storing Trimix Injections 

To ensure the maximum potency and safety of Trimix injections, here are some best practices for storing the medication:

Ensure Proper Temperature Control And Light Protection

Be sure to store Trimix injections in a cool, dark location that’s away from any heat sources and direct light exposure. This will prevent the medication from degrading prematurely and losing its potency. 

Use Proper, Airtight, And Moisture-Resistant Containers

Trimix injections should be stored in airtight and moisture-resistant containers to prevent oxidation and maintain their chemical stability. It is recommended to use the original container provided by the compounding pharmacy, as it is specifically designed for this purpose.

Keep Storage Locations Dark And Securely Tight

Keeping the storage location for Trimix injections dark and securely tight is essential. This will prevent any potential light exposure or contamination from outside elements, ensuring the medication’s potency and safety.

Use Refrigeration And Freezing

Storing Trimix in the refrigerator is the best way to ensure the medication’s maximum shelf life and potency. Doing so will allow the medication to last several weeks. If you need to store it for longer, freezing is an option.  However, once thawed after being frozen, they cannot be frozen again, or the medication will lose its effectiveness. 

If you need to travel with Trimex, you may request a specialized travel kit from the compounding pharmacy as the medication must still be kept in refrigerated temperatures even if it is frozen before travel. 

Rotate Stock Regularly

Regularly rotating your stock of Trimix will make it easier to avoid using expired injections. Use the oldest medication first and replace it with a fresh batch to ensure that you always have a supply of potent and safe Trimix injections. Once they reach the beyond-use date, do not use them, and ensure you discard them.

Monitor Long-Term Stability And Regular Quality Checks

Monitoring the long-term stability of Trimix injections and regularly performing quality checks is essential. This will ensure the medication remains potent and safe for use over an extended period. If there are any changes in appearance, consistency, or smell, do not use the medication – and consult with your healthcare provider.

Common Storage Mistakes You Should Avoid

Correctly storing Trimix injections is vital for their effectiveness and safety. Here are some common storage mistakes that you should avoid:

Exposing Injections To Light And Extreme Temperatures

Exposure to light and extreme temperatures can cause Trimix injections to degrade and lose their potency. Store them in a dark, cool place within the recommended temperature range.

Selecting An Inadequate Container and Sealing Insufficiently

Using improper containers or not sealing them securely can lead to air and moisture exposure, which can cause oxidation and affect the medication’s potency. Always use airtight and moisture-resistant containers.

Incorrect Storage Locations

Storing Trimix injections in areas with high humidity or near heat sources can cause them to degrade prematurely. You should choose an appropriate storage location that meets the recommended temperature and light exposure guidelines.

Why Opt For A Reputable Pharmacy When Sourcing Trimix 

Since Trimix is a compound medication, it means that it’s not FDA-approved. This is because it is specifically formulated and prepared by compounding pharmacies to meet individual patients’ unique needs. Therefore, when sourcing Trimix injections, it is critical to choose a reputable pharmacy that specializes in compound medications, for the following reasons:

  • Assurance of potency and stability: A reputable pharmacy will maintain strict quality control measures, thereby ensuring the potency and long-term stability of Trimix injections. They will also abide by all regulations and guidelines set by the USP (United States Pharmacopeia).
  • Customized formulations: Compounding pharmacies can tailor the Trimix formulation according to your specific needs and preferences (based on your doctor’s prescription). This personalized approach will ensure that the medication is effective for you and minimizes the risk of any adverse reactions.
  • Pharmacy compounding experience: Pharmacy compounding is a specialized skill that requires extensive training and knowledge. Reputable pharmacies will have trained and experienced pharmacists who are experts in creating compound medications like Trimix.
  • Ensuring patient safety through proper storage: As discussed above, proper storage of Trimix injections is crucial for their potency and safety. Reputable pharmacies will have the necessary facilities and protocols in place to ensure that the medication is stored correctly at all times. They will also ensure it is shipped and delivered to you in proper packaging that maintains the medication’s integrity.

We Align Our Trimix Injection Storage Approach With The Highest Industry Standards

At University Compounding Pharmacy, we understand the importance of proper storage when it comes to compound medications like Trimix injections. That is why we adhere to the highest industry standards and have stringent quality control and safety measures to ensure that our Trimix injections are potent, stable, and safe. Here’s how we align our storage approach with these standards:

  • PCAB certification: We are proud to be a PCAB (Pharmacy Compounding Accreditation Board) certified pharmacy, which means we must achieve and maintain the highest ethical and quality standards of not just the PCAB, but also the USP, FDA, and state pharmacy boards, by regularly testing and verifying our processes, equipment, and personnel against the most stringent standards.
  • State-of-the-art facilities: All of our facilities and equipment are ISO & USP compliant. Every room in our facilities complies with USP 795 and 797 regulations, all our sterile bench hoods are ISO 5 compliant, and many of our rooms are Class 7 certified clean rooms.
  • Trained pharmacists: Our team of pharmacists undergoes extensive training in compounding medications and stays updated with the latest techniques and guidelines.
  • Regular quality checks: We perform regular quality checks on our Trimix injections to ensure their potency and stability. In fact, we invest $30,000 a month on third-party testing to ensure the safety and efficacy of our medications.

Ensure Premium Quality With University Compounding Pharmacy’s Trimix Injections

By choosing University Compounding Pharmacy for your Trimix injections, you can be assured of receiving high-quality medications that have been tailored to your specific requirements and have been stored according to the best industry standards. Trust University Compounding Pharmacy for all your compound medication needs and experience the difference in quality and personalized care.


Start your optimal health with University Compounding Pharmacy’s quality Trimix injections.