Evaluating Penile Injections For ED, aka Erectile Dysfunction

Erectile dysfunction (ED) is a very common issue affecting millions of men worldwide. When faced with this condition, many men are desperate to find a solution that will restore their sexual function, thereby improving their overall quality of life. Although there are many treatment options available, including oral medications, penile injections have gained popularity in recent years as a highly effective and personalized approach to treating ED. 

The following is a brief guide to understanding what penile injections are, how they work, and their potential benefits for men struggling with ED.

Understanding Erectile Dysfunction

ED is characterized by a man’s inability to either achieve or maintain an erection that is sufficient for sexual intercourse. ED can have a significant impact on a man’s physical, emotional, and psychological well-being, as well as his intimate relationships.

Several factors can contribute to the development of ED, including lifestyle choices, medical conditions, and medications. Some common risk factors include obesity, smoking, diabetes, high blood pressure, heart disease, and certain neurological disorders. However, ED can also be a result of psychological factors, which can include anxiety, depression, and stress.

The Three Main Types Of Penile Injection Shots Used As Treatment Options For ED

Penile injections, also known as intracavernosal injections, are medications that can address ED by being injected directly into the penis using a small needle. This approach allows for the medicine to quickly enter the bloodstream and produce an erection within 5-20 minutes. 

This method of treatment has been used for decades and has proven to be incredibly effective in managing ED. The following are the three main types of injectables used for ED:


Papaverine is a drug that belongs to the class of vasodilators, which means it helps widen blood vessels. Papaverine works by relaxing the smooth muscles in the penis. Smooth muscles are muscles that are not under our conscious control, and they are found in the walls of blood vessels. In the penis, they are responsible for controlling the blood flow and thus play a crucial role in achieving and maintaining an erection. By relaxing these muscles, papaverine allows for increased blood flow to the penis, thereby leading to a firmer and longer-lasting erection.


Phentolamine is another type of vasodilator that also relaxes the smooth muscles in the penis. However, unlike papaverine, phentolamine acts as a non-selective alpha-blocker, meaning it blocks certain receptors in the body that cause the constriction of blood vessels. By blocking these receptors, phentolamine helps increase blood flow to the penis, thereby resulting in an erection.

Alprostadil (Prostaglandin E1)

Alprostadil, also known as prostaglandin E1, is a synthetic form of a naturally occurring hormone. Alprostadil helps relax the smooth muscles in the penis and dilate blood vessels to increase blood flow. Additionally, alprostadil can also affect nerve signals that are involved in the erectile response, further aiding in achieving and maintaining an erection.

Benefits Of Penile Injections As A Treatment For ED

At first glance, you may feel hesitant or even intimidated by the idea of injecting medication directly into your penis – especially when there are oral medications available. However, penile injections offer several benefits that make them a desirable option for men struggling with ED:

Quick Onset Of Action

One of the primary benefits of using penile injections is the speed at which they work. Unlike oral medications, which often take upwards of an hour to take effect, injectables can achieve an erection within 5-20 minutes, depending on the individual and dosage used. This makes them an ideal treatment option for men who want to be spontaneous and don’t want to plan their sexual activity around medication.

High Success Rates

Penile injections are highly effective in treating ED, with success rates ranging from 70-80%. This is significantly higher than oral medications, which have a success rate of around 50%. 

Minimal Systemic Side Effects

Certain oral ED medications, such as Viagra and Cialis, can cause various side effects, such as headaches, upset stomachs, and vision changes. Since penile injections are administered locally and directly into the penis, they have a lower risk of causing systemic side effects.

How To Administer ED Injections

Administering ED injections may seem daunting at first, but with proper training and guidance from a healthcare professional, it can be easily done at home. The following steps should be followed for safe and effective self-administration of penile injections:

  • Preparation: Before injecting the medication, make sure you have everything you need, including the prescribed medication, syringes, alcohol wipes, and a sharps container. Be sure to thoroughly wash your hands using warm water and soap.
  • Proper dosage: It is essential to use the correct dosage as prescribed by your doctor. Do not increase or decrease the dosage without consulting your healthcare provider.
  • Selecting the injection site: The most common injection site is on the side of the penis shaft, about 1-2 inches from the base. Be sure to rotate injection sites as well to avoid scar tissue buildup.
  • Cleaning the injection site: Use an alcohol wipe to clean the skin at the injection site and let it dry completely.
  • Injecting the medication: Hold the syringe like a pen and insert the needle into the selected injection site at a 90-degree angle. Slowly push the plunger down to inject the ED medication. Then carefully remove the needle at the angle it was inserted.
  • Applying pressure and massaging: Apply pressure with a sterile gauze to the injection site for a few minutes to prevent any bleeding. Gently massage the area to help spread the medication and promote absorption.

Where To Get Your Erectile Dysfunction Injections

When considering penile injections as a treatment for ED, it is vital to consult with a healthcare provider first. They can evaluate your medical history to determine if this ED treatment option is suitable for you. Additionally, they can provide proper training and guidance on how to self-administer the penile injections safely and effectively.

Once you have been prescribed penile injections, there are several options for obtaining them:

  • Local pharmacy: Many local pharmacies carry ED medications, including penile injections.
  • Online pharmacies: Some online pharmacies also offer ED medications, including injectables. However, it is crucial to do thorough research and only purchase from an online pharmacy that is reputable and licensed, to avoid counterfeit or substandard medications.
  • Compounding pharmacies: Compounding pharmacies specialize in creating customized medications to meet individual needs. They can create penile injections with specific dosages and combinations of medication as prescribed by your doctor.

It is essential to follow all instructions from your healthcare provider and only obtain ED injections from a trusted source to ensure optimal results and minimize the risk of side effects. 

Trimix Injections Available At University Compounding Pharmacy

At University Compounding Pharmacy, we understand that every patient’s needs are unique when it comes to treating ED. That’s why we offer personalized solutions like Trimix injections. Trimix is a blend of three medications, including alprostadil, papaverine, and phentolamine, that work together to improve the blood flow to your penis and produce an erection.

Our team of pharmacists works closely with your healthcare provider to create a customized blend of medications specific to your individual needs and desired results. Our pharmacists are trained to compound Trimix injections with precise dosages tailored to each patient’s requirements. Additionally, we provide detailed instructions on proper usage and storage of the medication for optimal results. 

Make Informed Medical Decisions With Us

Making an informed medical decision is crucial when it comes to treating erectile dysfunction. We understand that this can be a sensitive and overwhelming issue, but rest assured, we are here to support you every step of the way.

Remember, always consult with your healthcare provider before you decide to use any type of ED treatment, including penile injections. They will give you valuable insight and guidance that is tailored to your specific needs.

At University Compounding Pharmacy, we are committed to providing personalized and effective solutions for ED. Our team of pharmacists is highly trained in compounding medications and dedicated to creating customized treatments that meet our patients’ unique requirements.

Your journey to improved intimacy begins here. Take charge of your sexual health with University Compounding Pharmacy’s Trimix Injections.