Exploring Compounded Semaglutide: Safety, Legality, and More

In this blog post, we will uncover what compounded semaglutide is, its safety, sourcing, and how to get your hands on this potentially transformative medication.

What is Compounded Semaglutide?

Compounded semaglutide is a unique variant of the widely recognized medication, semaglutide. The defining characteristic of compounded semaglutide lies in its fusion of traditional semaglutide with other body-safe vitamins, such as B12. Semaglutide, a GLP1 receptor agonist, was initially engineered to combat diabetes by regulating blood glucose levels through the stimulation of insulin release. However, its journey didn’t stop there. In June 2021, it secured FDA approval as a weight loss medication for patients grappling with obesity, thus expanding its horizons beyond diabetes management. In addition to its insulin-boosting properties, semaglutide extends the digestive process, resulting in prolonged feelings of fullness in patients following a meal. 

Are there Legal Concerns? 

A noteworthy development in the landscape of semaglutide is that commercial semaglutide has recently found itself on the FDA shortage list. This intriguing turn of events has bestowed upon compounding pharmacies, the legal sanction to offer compounded semaglutide—a game-changer poised to significantly enhance patient care.

Who Makes Compounded Semaglutide?

Safety is a key concern when selecting a compounding pharmacy in the sourcing of compounded semaglutide. University Compounding Pharmacy based in Troy, Michigan, has been in business for over 20 years and has over a year of experience in the compounding of semaglutide. Safety is a paramount concern when it comes to any medication, and compounded semaglutide is no exception. As a PCAB-accredited pharmacy, University Compounding Pharmacy spends $30,000 monthly on testing to ensure patient safety with the highest quality medication. Every batch that is produced undergoes testing by a third party before being made available to patients.

At University Compounding Pharmacy, compounded semaglutide is available in the following doses: 

  • Semaglutide/Cyanocobalamin 2mg-0.4mg/mL 1mL vial
  • Semaglutide/Cyanocobalamin 5mg-0.4mg/mL 2mL vial 

Are There Safety Concerns? 

By federal law, compounding pharmacies must source API (Active Pharmaceutical Ingredient)

from FDA-registered and inspected facilities. This API comes with a certificate of analysis (COA) that breaks down the substance’s identity, potency, and purity. Patients and prescribers who want to be extra sure about the dispensed drug’s authenticity can request to check out the COA at the compounding pharmacy of their choosing. It’s a solid way to ensure that what’s being given to patients aligns with the pharmacy’s claims.

Contact University Compounding Pharmacy Today!

Finding a trustworthy source for compounded semaglutide is crucial. Compounded medications should always be obtained from PCAB-accredited pharmacies like University Compounding PharmacyFor more information on obtaining a prescription or prescribing compounded semaglutide from University Compounding Pharmacy, visit our weight loss page. 

In conclusion, semaglutide can be legally compounded by compounding pharmacies in accordance with FDA guidelines. At University Compounding Pharmacy, compounded semaglutide is prepared with care and adheres to strict safety and quality standards. Compounded semaglutide provides an alternative for those who have been unable to obtain the commercially available medication due to shortages. Always consult your healthcare provider to determine the most suitable treatment plan for your specific needs.


  1. FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 | FDA. Accessed September 13, 2023

  2. Drug Shortages | FDA. Accessed September 13, 2023